Oxazole Blue, 1 mM in DMSO
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Oxazole blue, also known as PO-PRO™-1, is a blue-fluorescent dead cell stain. This dye is a cell-impermeant nucleic acid stain with excitation/emission maxima of 435/455 nm when bound to nucleic acids.
| SIZE |
CATALOG #
|
PRICE
|
|
1 mL |
#40091 |
$310 |
PRODUCT ATTRIBUTES
| ellular localization |
Nucleus |
|---|---|
| Cell permeability |
Membrane impermeant |
| Colors |
Blue |
| Apoptosis/viability marker |
Dead cell stain |
| CAS number |
157199-56-9 |
| Excitation/Emission |
435/455 nm (with DNA) |
PRODUCT DESCRIPTION
Oxazole blue, also known as PO-PRO™-1, is a blue-fluorescent dead cell stain. This dye is a cell-impermeant, high-affinity carbocyanine monomeric nucleic acid stain that is essentially nonfluorescent in the absence of nucleic acids but exhibits excitation/emission maxima 435/455 nm when bound to nucleic acids.
- Monomeric nucleic acid stain
- Cell-impermeant
- Dead and apoptotic cell indicator
- λEx/λEm (with DNA) = 435/455 nm
- C20H27I2N3O
- MW: 579.26
- Cas#: 157199-56-9
- Supplied at 1 mM in DMSO
PO-PRO is a trademark of Thermo Fisher Scientific.
Reference Publications
Ashley D. Nemes-Baran, Donovan R. White, Tara M. DeSilva
Fractalkine-Dependent Microglial Pruning of Viable Oligodendrocyte Progenitor Cells Regulates Myelination
Cell reports vol. 32,7 (2020): 108047.
DOI: 10.1016/j.celrep.2020.108047
Article Snippet: “Oxazole blue/DilC1(5) dyes (oxazole blue 455, DilC1(5) 658, Biotium Inc., Fremont, CA) were used in acute experiments with ex-vivo brain slices to confirm cell viability of engulfed and contacted cells.”
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