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Mesenchymal Stem Cells as a Drug Delivery Vehicle for Brain Tumour

Cancer is a disease that can develop anywhere in our body as a result of excessive cell division. The location and cell types influence the etiology, symptoms, severity, and therapeutic approaches. In brain tumours, more than 75% of adults are affected by glioblastoma. The average survival rate is only two years after diagnosis, and the progression of therapeutic strategies is limited and challenging. These are mainly due to the blood-brain barrier (BBB) blockage, which makes intravenous chemotherapeutic compounds difficult to get through, and the relative rarity of this kind of cancer, which makes it difficult to attract pharmaceutical companies.

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What are MSC Spheroids, Why it Matters, & How to Culture It for Regenerative Medicine Studies?

Stem cell therapy is one of the most promising approaches in the field of regenerative medicine. It is to promote the repair response of the diseased or injured tissue to restore the lost function. Many diseases can be targeted by cell therapy. These include blood-related diseases, neuronal degenerative diseases, ischemic and cardiovascular disorders, bone and cartilage diseases, wound healing, etc. 

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3D Culture

In vitro three-dimensional (3D) cell cultures have been increasingly used for drug discovery, tissue engineering, cancer research, stem cell research and regenerative medicine.

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Cellular Imaging

Cancer is a leading cause of death worldwide, with an estimated 10 million of cancer death in 2020. It is a disease that originates from uncontrollable growth of abnormal cells which can spread to other parts of the body to form new tumours, a process known as metastasis. During the past 250 years

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Microfluidics

Microfluidics is the technology of manipulating small volumes of fluids in channels with dimensions at the microscale – typically tens to hundreds of micrometres and is known as lab-on-a-chip.

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Exosome Research

Exosomes are nano-sized extracellular vesicles ranging 30-150 nanometers. They are readily released by most cells and can be found in all body fluids including plasma, serum, saliva, cerebrospinal fluid, urine and cell culture media.

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