Cre/Dre Mice

Organ/system Subclassification：

STRAIN NO.	STRAIN NAME	PROMOTER	THEORETICAL ORGAN/SYSTEM EXPRESSION	SUBCLASSIFICATION	THEORETICAL LABELED CELL TYPE	PUBLISHED LITERATURE
T003814	Alb-iCre	Alb	Liver		Hepatic cells	Yes
T007670	B6-Pdx1-iCre	Pdx1	Alimentary system Endocrine system	Alimentary system-Stomach Alimentary system-Pancreas Alimentary system-Small intestine	Pancreatic ductal epithelial cells, islet cells, parietal cells and duodenal epithelial cells	Yes
T005640	Csf1r-IRES-iCre	Csf1r	Immune system	Immune system-Monocytes & macrophages Immune system-Dendritic cells	Dendritic cells, monocytes, macrophages	Yes
T006187	Cspg4-CreERT2	Cspg4	Circulation system Nervous system	Circulation system-Others Nervous system-Supportive cells	Perivascular cells and gliocytes	Yes
T006768	Cx3cr1-iCre	Cx3cr1	Immune system Nervous system	Immune system-T lymphocytes Immune system-Monocytes & macrophages Immune system-NK cells Nervous system-Supportive cells	Monocytes, macrophages, microglial cells, NK cells, CD8+ T cells	Yes
T055137	Gja10-iCre	Gja10	Sensory organs		Retina, crystalline lens	Yes
T006950	H11-Ctsk-iCre	Ctsk	Motor & skeletal system	Motor & skeletal system-Bone/cartilage	Osteoclasts	Yes
T004857	H11-Gfap-iCre	Gfap	Nervous system	Nervous system-Supportive cells	Astrocytes of the central Nervous system	Yes
T004819	H11-Itgax-iCre	Itgax	Immune system	Immune system-NK cells Immune system-Dendritic cells	Dendritic cells, NK cells, etc	Yes
T004713	H11-Myh6-iCre	Myh6	Circulation system	Circulation system-Myocardium	Almost all mature cardiomyocytes	Yes
T052699	H11-Syn1-iCre	Syn1	Nervous system Reproductive system	Nervous system-Corpus striatum Reproductive system-Female reproductive organs reproductive organs Nervous system-Cortex	Widely expressed in brain, relatively low in corpus striatum and high in cortex	Yes
T004714	H11-Vil1-iCre	Vil1	Alimentary system	Alimentary system-Large intestine Alimentary system-Small intestine	Epithelial cells in gastrointestinal tract and Urinary system	Yes
T004833	H11-hKRT14-iCre	KRT14	Sensory organs		Cells in ectodermal differentiated tissues such as skin, keratinocytes, oral epithelium, etc.	Yes
T003768	Lgr5-creERT2	Lgr5	Alimentary system Uncategorized	Alimentary system-Stomach Alimentary system-Large intestine Alimentary system-Small intestine Uncategorized-Application scenary identified	Simple columnar epithelial cells (intestinal stem cells) and colon stem cells, gastric glandular epithelial stem cells, mammary gland stem cells(basal cells)	Yes
T006205	Lrat-P2A-iCre	Lrat	Liver		Hepatic stellate cells	Yes
T003822	Lyz2-icre	Lyz2	Immune system	Immune system-Granulocytes Immune system-Monocytes & macrophages Immune system-Dendritic cells	Myeloid cells (including monocytes, macrophages, granulocytes, mastocytes, and some dendritic cells, etc.)	Yes
T005674	Ncr1-iCre-P2A	Ncr1	Immune system	Immune system-NK cells	NK cells	Yes
T004715	Sftpc-IRES-iCre	Sftpc	Respiratory system		Alveolar type II cell	Yes
T003764	Tek-iCre	Tek	Circulation system	Circulation system-Hematopoietic cell lineage Circulation system-Vascular/lymphatic endothelium	Endothelial cells (blood vessels, lymph vessels, endocardium), some hematopoietic stem cells and blood cells	Yes
T053168	1700028K03Rik-HA-P2A-CreGFP	1700028K03Rik	Uncategorized	Uncategorized-Application under discovery	1700028K03Rik+ cells, application under discovery	No

STRAIN NO.	STRAIN NAME	PROMOTER	THEORETICAL ORGAN/SYSTEM EXPRESSION	SUBCLASSIFICATION	THEORETICAL LABELED CELL TYPE	PUBLISHED LITERATURE
T055140	Acan-P2A-CreERT2	Acan	Motor & skeletal system	Motor & skeletal system-Bone/cartilage	Fibrochondrocytes in growth plate, articular cartilage, meniscus, trachea and intervertebral disc	No
T004711	Adipoq-P2A-iCre	Adipoq	Adipose tissue		White adipose tissue	No
T004894	Aif1-CreERT2	Aif1	Reproductive system	Reproductive system-Male reproductive organs	Testis	No
T055035	Alb-IRES-iCre	Alb	Liver		Hepatic cells	No
T052693	Aldh1l1-CreERT2	Aldh1l1	Nervous system	Nervous system-Supportive cells	Astrocytes, oligodendrocytes	No
T006926	Aldh1l1-P2A-iCre	Aldh1l1	Nervous system	Nervous system-Supportive cells	Astrocytes, oligodendrocytes	No
T007700	Amh-P2A-iCre	Amh	Reproductive system	Reproductive system-Female reproductive organs Reproductive system-Male reproductive organs	Sertoli cells, spermatids, epididymal and seminiferous epithelial cells, follicle cells, oocytes, etc	No
T036905	Angptl7-P2A-CreERT2	Angptl7	Motor & skeletal system Urinary system Reproductive system	Motor & skeletal system-Skelatal muscle Reproductive system-Male reproductive organs Reproductive system-Female reproductive organs	Chondrocytes	No
T004733	Apln-iCre	Apln	Circulation system	Circulation system-Vascular/lymphatic endothelium	Vascular endothelial cell	No
T051578	Aqp5-CreERT2-EGFP	Aqp5	Respiratory system Alimentary system	Alimentary system-Others	Epithelial cells in salivary gland and lung, etc.	No
T054674	Atp4b-iCre	Atp4b	Alimentary system	Alimentary system-Stomach	Parietal cells	No
T053984	Axin1-P2A-CreERT2	Axin1	Uncategorized	Uncategorized-Application under discovery	Axin1+ cells, application under discovery	No
T052696	Bmi1-P2A-CreERT2	Bmi1	Alimentary system	Alimentary system-Small intestine	Epithelial cells in small intestinal crypt	No
T006946	Brs3-P2A-iCre	Brs3	Nervous system	Nervous system-Others	Parabrachial nuclei	No
T006202	Calb1-P2A-iCre	Calb1	Nervous system	Nervous system-Hippocampus Nervous system-Corpus striatum Nervous system-Thalamus/hypothalamus Nervous system-Brainstem	Some cells in hippocampus, corpus striatum, thalamus, hypothalamus, midbrain, pons, medulla and cerebellum	No
T004855	Cck-IRES-iCre	Cck	Nervous system	Nervous system-Hippocampus Nervous system-Cortex Nervous system-Thalamus/hypothalamus	Widely expressed in the cortex, hippocampus, and thalamus; other areas of the brain have sparse, dispersed expression; the Purkinje cell layer in the cerebellum is highly expressed; enriched in restricted pons and medulla populations	No
T003785	Cd19-icre	Cd19	Immune system	Immune system-B lymphocytes	B cells	No
T051224	Cd209e-P2A-iCre-P2A-tdTomato	Cd209e	Immune system	Immune system-Dendritic cells	Dendritic cells	No
T055138	Cd34-P2A-CreERT2	Cd34	Circulation system	Circulation system-Hematopoietic cell lineage	Cd34+ hematopoietic stem cells, activated inflammatory cells	No
T055135	Cd4-IRES-iCre	Cd4	Immune system	Immune system-T lymphocytes	Helper T cells (CD4+ T cells)	No

STRAIN NO.	STRAIN NAME	PROMOTER	THEORETICAL ORGAN/SYSTEM EXPRESSION	SUBCLASSIFICATION	THEORETICAL LABELED CELL TYPE	PUBLISHED LITERATURE
T007046	Cdh16-CreERT2	Cdh16	Urinary system		Renal tubular epithelial cells	No
T052686	Cdh5-P2A-CreERT2	Cdh5	Circulation system	Circulation system-Vascular/lymphatic endothelium	Vascular endothelial cells	No
T006965	Cep295nl-P2A-Cre	Cep295nl	Reproductive system	Reproductive system-Male reproductive organs	Testis	No
T055158	Chat-iCre	Chat	Nervous system	Nervous system-Hippocampus Nervous system-Corpus striatum Nervous system-Thalamus/hypothalamus Nervous system-Amygdala Nervous system-Olfactory bulb	Brainstem (thalamus, basal ganglion), basal forebrain (hippocampus, olfactory bulb, amygdala), corpus striatum and cholinergicneurons	No
T056749	Cldn18-IRES-CreERT2	Cldn18	Alimentary system Respiratory system	Alimentary system-Stomach	Lung, stomach	No
T036801	Clec4f-IRES-iCre	Clec4f	Liver		Kupffer cells	No
T053653	Clu-P2A-CreERT2-P2A-EGFP	Clu	Uncategorized	Uncategorized-Application scenary identified	Upregulated in cells undergoing inflammatory stress or genomic damage stress	No
T055147	Cntnap2-P2A-CreERT2-P2A-mCherry	Cntnap2	Nervous system	Nervous system-Hippocampus Nervous system-Corpus striatum Nervous system-Cortex	Embryonic prefrontal cortex, hippocampus, corpus striatum; GABAergic interneurons, excitatory pyramidal neurons	No
T006204	Csf1r-P2A-CreERT2	Csf1r	Immune system	Immune system-Monocytes & macrophages Immune system-Dendritic cells	Dendritic cells, monocytes, macrophages	No
T052701	Cxcl1-P2A-iCre	Cxcl1	Immune system	Immune system-Monocytes & macrophages	Bone marrow macrophages	No
T055139	Cyp17a1-P2A-iCre	Cyp17a1	Reproductive system	Reproductive system-Female reproductive organs reproductive organs Reproductive system-Male reproductive organs	Theca-interstitial cells and leydig cells	No
T055388	Dclk1-CreERT2-IRES-EGFP-polyA	Dclk1	Nervous system Alimentary system Respiratory system	Nervous system-Hippocampus Alimentary system-Stomach Alimentary system-Large intestine Alimentary system-Pancreas Nervous system-Cortex	Colorectum, bile duct, stomach, pancreas, lung, hippocampus, nucleus accumbens, prefrontal cortex	No
T050097	Dmbt1-rox-stop-rox-P2A-iCre	Dmbt1	Alimentary system	Alimentary system-Stomach Alimentary system-Pancreas Alimentary system-Large intestine Alimentary system-Small intestine	Gastrointestinal tract, pancreas	No
T052793	Drd1-iCre	Drd1	Nervous system	Nervous system-Corpus striatum Nervous system-Cortex	Highly expressed in ampler piriform (pear-shaped) cortex and corpus striatum; restrictly expressed in medulla, pons and cerebellum	No
T052794	Drd2-iCre	Drd2	Nervous system	Nervous system-Corpus striatum Nervous system-Cortex Nervous system-Thalamus/hypothalamus Nervous system-Olfactory bulb	Expressed primarily in corpus striatum, seldom in cerebellum, cortex, thalamus, medulla and olfactory bulb	No
T050695	Ebf1-icre	Ebf1	Immune system	Immune system-B lymphocytes	B cells	No
T006195	Elane-iCre	Elane	Immune system	Immune system-Granulocytes Immune system-Monocytes & macrophages	Granulocytes-monocyte progenitors, neutrophils, monocytes, macrophagess	No
T055046	Elane-iCre-P2A-EGFP	Elane	Immune system	Immune system-Granulocytes Immune system-Monocytes & macrophages	Granulocytes-monocyte progenitors, neutrophils, monocytes, macrophages	No
T052704	Elf5-P2A-iCre	Elf5	Uncategorized Reproductive system Endocrine system Sensory organs	Uncategorized-Application scenary identified Reproductive system-Male reproductive organs	Mammary gland, salivary gland, skin, prostate, adrenal gland	No
T054663	En1-IRES-creERT2	En1	Nervous system	Nervous system-Brainstem Nervous system-Others Nervous system-Spinal cord Nervous system-Cerebellum	Mesencephalon and rhombomere, as well as the developing cerebellum, dermis, and limbs	No

STRAIN NO.	STRAIN NAME	PROMOTER	THEORETICAL ORGAN/SYSTEM EXPRESSION	SUBCLASSIFICATION	THEORETICAL LABELED CELL TYPE	PUBLISHED LITERATURE
T053982	En1-P2A-iCre	En1	Nervous system	Nervous system-Brainstem Nervous system-Others Nervous system-Spinal cord Nervous system-Cerebellum	Mesencephalon and rhombomere, as well as the developing cerebellum, dermis, and limbs	No
T052749	Epor-P2A-iCre-P2A-EGFP	Epor	Circulation system	Circulation system-Hematopoietic cell lineage	erythroid progenitor cells	No
T053613	Epx-IRES-iCre	Epx	Immune system	Immune system-Granulocytes	Eosinophils	No
T056043	Etv1-P2A-iCre	Etv1	Circulation system Nervous system Sensory organs	Circulation system-Myocardium Nervous system-Others	ER81+neurons (including L5 of pyramidal neurons), myocardial cells, retinal ganglion cells and inner nuclear layer cells	No
T058048	Fn1-CreERT2	Fn1	Uncategorized	Uncategorized-Application scenary identified	Fn1+ cells like dorsal subiculum neurons, etc	No
T052797	Fos-CreERT2	Fos	Nervous system	Nervous system-Hippocampus Nervous system-Cortex Nervous system-Amygdala Nervous system-Supportive cells	Hippocampus, amygdala and subplate, especially in the deep cortical layer	No
T052687	Foxg1-P2A-iCre	Foxg1	Nervous system	Nervous system-Others	Early expression begins in the telencephalon at E8.5-E9.0. Followed by expresion in ear vesicle, anterior half of the optic capsule, pharyngeal endoderm and foregut at E10.5.	No
T006185	Gcg-IRES-CreERT2	Gcg	Endocrine system		Pancreatic α-cells, enteroendocrine cells and some neurons	No
T055136	Gcg-P2A-iCre	Gcg	Endocrine system		Pancreatic α-cells, enteroendocrine cells, some neurons	No
T053866	Gfap-P2A-Dre	Gfap	Nervous system	Nervous system-Supportive cells	Astrocytes of the central Nervous system	No
T052707	Ghrl-P2A-iCre	Ghrl	Alimentary system	Alimentary system-Stomach Alimentary system-Pancreas Alimentary system-Large intestine Alimentary system-Small intestine	Gastrointestinal tract, pancreas	No
T050098	Gkn1-rox-stop-rox-P2A-iCre	Gkn1	Alimentary system	Alimentary system-Stomach	Stomach	No
T051137	Gnb4-P2A-CreERT2-P2A-mEGFP	Gnb4	Nervous system	Nervous system-Cortex Nervous system-Thalamus/hypothalamus	Cortex, thalamus, hypothalamus	No
T006924	Grik2-P2A-iCre	Grik2	Nervous system	Nervous system-Hippocampus Nervous system-Cortex Nervous system-Thalamus/hypothalamus Nervous system-Brainstem	Almost ubiquitous in brain	No
T017784	H11-Alb-CreERT2	Alb	Liver		Hepatic cells	No
T052677	H11-BEST1-iCre-SV40 Intron	BEST1	Sensory organs		Retinal pigment epithelium, muller cells	No
T006947	H11-C1ql2-iCre	C1ql2	Nervous system	Nervous system-Thalamus/hypothalamus	Excitatory neurons in the anterodorsal subganglion of the thalamus	No
T049745	H11-CAG-Dre-WERP-PolyA	CAG	Ubiquitous		Ubiquitous expressed	No
T049774	H11-CAG-DreERT2-WPRE-PolyA	CAG	Ubiquitous		Ubiquitous expressed	No
T054722	H11-Camk2a-iCre-polyA	Camk2a	Nervous system	Nervous system-Cortex Nervous system-Others	Forebrain, CA1 pyramidal neurons	No

STRAIN NO.	STRAIN NAME	PROMOTER	THEORETICAL ORGAN/SYSTEM EXPRESSION	SUBCLASSIFICATION	THEORETICAL LABELED CELL TYPE	PUBLISHED LITERATURE
T004818	H11-Cd4-iCre	Cd4	Immune system	Immune system-T lymphocytes	Helper T cells (CD4+ T cells), cytotoxic T cells(CD4+CD8+ T cells)	No
T004820	H11-Cdh16-iCre	Cdh16	Urinary system		Renal tubular epithelial cells(primarily in distal renal tubule for those in the proximal tubule are less efficient)	No
T004712	H11-Cdh5-iCre	Cdh5	Circulation system	Circulation system-Vascular/lymphatic endothelium	Vascular endothelial cell	No
T004734	H11-Col1a1-iCre	Col1a1	Motor & skeletal system	Motor & skeletal system-Bone/cartilage Motor & skeletal system-Skeletal muscle	Cells in connective tissues such as cornea, tendons, etc; osteoblasts	No
T014706	H11-Col2a1-β-globin intron-CreERT2-polyA	Col2a1	Motor & skeletal system	Motor & skeletal system-Bone/cartilage	Chondrocytes	No
T004830	H11-Dmp1-iCre	Dmp1	Motor & skeletal system	Motor & skeletal system-Bone/cartilage	Odontoblasts, osteoblasts, osteocytes	No
T004831	H11-Fabp4-iCre	Fabp4	Adipose tissue		Mainly active in brown and white adipose cells, however this strain also displays activity in skeletal muscle cells, cardiomyocytes, macrophagess, etc.	No
T004832	H11-KRT5-iCre	KRT5	Urinary system Sensory organs Alimentary system Reproductive system	Alimentary system-Others Reproductive system-Male reproductive organs	Basal cells of the epidermis, corneal cells, esophageal epithelium, prostate, bladder, some spontaneous breast and lung cancer cells, etc.	No
T005635	H11-MMTV-iCre	MMTV	Alimentary system Reproductive system Sensory organs Immune system	Alimentary system-Others Reproductive system-Male reproductive organs Immune system-T lymphocytes Immune system-B lymphocytes	Mammary gland, salivary gland, seminal vesicle, skin, T cells, B cells and erythrocytes	No
T004821	H11-Mx1-iCre	Mx1	Immune system	Immune system-Others	With IFN-α, IFN-β, or dsRNA induction, it is highly expressed in INF-responsive cells such as lymphocytes and macrophagess. Lack of activity in the absence of stimulation.	No
T004858	H11-Myh6-CreERT2	Myh6	Circulation system	Circulation system-Myocardium	Almost all mature cardiomyocytes	No
T004010	H11-Myl2-CreERT2-P2A-tdTomato	Myl2	Circulation system	Circulation system-Myocardium	Adult cardiomyocytes	No
T005680	H11-Nphs1-iCre	Nphs1	Urinary system		Glomerular podocytes	No
T004859	H11-Pax8-CreERT2	Pax8	Urinary system		Renal tubule	No
T005638	H11-Pbsn-iCre	Pbsn	Reproductive system	Reproductive system-Male reproductive organs	Prostate	No
T004860	H11-Pdx1(Ipf1)-Cre	Pdx1	Alimentary system Endocrine system	Alimentary system-Stomach Alimentary system-Pancreas Alimentary system-Small intestine	Pancreatic ductal epithelial cells, islet cells, parietal cells and duodenal epithelial cells	No
T052678	H11-Rat CCSP(Scgb1a1)-iCre	RatCCSP	Respiratory system		Lung, respiratory epithelial cells	No
T009409	H11-Stra8-iCre	Stra8	Reproductive system	Reproductive system-Female reproductive organs Reproductive system-Male reproductive organs	Seminiferous tubular epithelial cells, leydig cells, oogonia	No
T050817	H11-Thy1-iCre-IRES-ZsGreen	Thy1	Immune system Nervous system Sensory organs Circulation system	Immune system-T lymphocytes Nervous system-Hippocampus Nervous system-Cortex Circulation system-Hematopoietic cell lineage Circulation system-Vascular/lymphatic endothelium	Thymocytes, T cells, cortex, hippocampusneurons, retinal ganglion cells, fibroblast subtypes, perivascular cells, activated endothelial cells, mesangial cells, hematopoietic and mesenchymal stem cells	No
T004829	H11-Vil1-CreERT2	Vil1	Alimentary system	Alimentary system-Large intestine Alimentary system-Small intestine	Epithelial cells in gastrointestinal tract and Urinary system	No

STRAIN NO.	STRAIN NAME	PROMOTER	THEORETICAL ORGAN/SYSTEM EXPRESSION	SUBCLASSIFICATION	THEORETICAL LABELED CELL TYPE	PUBLISHED LITERATURE
T052705	H11-Zp3-iCre	Zp3	Reproductive system	Reproductive system-Female reproductive organs reproductive organs	Expressed in the oocytes before the first meiotic division	No
T052710	H11-hBGLAP-Rabbit beta-globin IVS2-iCre-Beta-actin 3’UTR	hBGLAP	Motor & skeletal system	Motor & skeletal system-Bone/cartilage	Osteoblasts	No
T004983	H11-hCD2-iCre	hCD2	Immune system	Immune system-T lymphocytes Immune system-Others Immune system-B lymphocytes Immune system-NK cells	Thymic epithelial cells and all lymphatic lineage cells (T, B, NK, and some dendritic cells)	No
T005671	H11-hDBH-iCre	hDBH	Nervous system	Nervous system-Brainstem Nervous system-Spinal cord Nervous system-Others	Adrenal gland	No
T005634	H11-hED-L2-iCre	ED-L2	Alimentary system	Alimentary system-Others	Esophagus epithelial cells	No
T005327	H11-hSTK11-iCre	hSTK11	Immune system	Immune system-T lymphocytes	Treg cells	No
T005672	H11-hTPO-iCre	hTPO	Endocrine system		Thyroid	No
T017785	Hopx-CreERT2	Hopx	Circulation system Alimentary system Liver Respiratory system	Circulation system-Myocardium Alimentary system-Large intestine Alimentary system-Small intestine	Intestinal epithelial cells and villus cells, some alveolar epithelial cells, myocardial cells, some parenchymal hepatic cells, etc	No
T037878	Iapp-iCre	Iapp	Alimentary system	Alimentary system-Pancreas	Pancreas	No
T050729	Igf1-P2A-CreERT2	Igf1	Liver		Liver cells	No
T006972	Il5-P2A-iCre	Il5	Immune system	Immune system-Others	Type II innate lymphoid cells	No
T004822	Ins1-iCre	Ins1	Endocrine system		Pancreatic β cell	No
T004817	Ins2-iCre	Ins2	Endocrine system		Pancreatic β cell	No
T050818	Itm2a-P2A-DreERT2	Itm2a	Motor & skeletal system	Motor & skeletal system-Skeletal muscle	Myofiber	No
T050819	Itm2a-P2A-iCre	Itm2a	Motor & skeletal system	Motor & skeletal system-Skeletal muscle	Myofiber	No
T052792	Kdr-P2A-iCre	Kdr	Circulation system	Circulation system-Vascular/lymphatic endothelium	Blood cells, vascular endothelial cells	No
T052689	Klrb1c-iCre-P2A	Klrb1c	Immune system	Immune system-NK cells	NK cells	No
T053524	Kng2-P2A-rox-stop-rox-iCre	Kng2	Uncategorized	Uncategorized-Application under discovery	Kng2+ cells, application under discovery	No
T056046	Krt19-DreERT2-polyA	Krt19	Uncategorized	Uncategorized-Application scenary identified	Epithelial cells in lung, oral cavity, bronchus, bronchiole, stomach, small intestine, pancreas, kidney, liver, etc.	No
T006978	Ly6a-P2A-iCre	Ly6a	Circulation system	Circulation system-Hematopoietic cell lineage Circulation system-Vascular/lymphatic endothelium	Vascular endothelial cells, some hematopoietic precursor cells	No

STRAIN NO.	STRAIN NAME	PROMOTER	THEORETICAL ORGAN/SYSTEM EXPRESSION	SUBCLASSIFICATION	THEORETICAL LABELED CELL TYPE	PUBLISHED LITERATURE
T054284	Ly6d-P2A-CreERT2	Ly6d	Immune system	Immune system-B lymphocytes	Ly6d+ cells, including some B cells	No
T004985	Lyve1-IRES-iCre	Lyve1	Circulation system	Circulation system-Vascular/lymphatic endothelium	Lymphatic endothelial cells	No
T052871	Lyz1-P2A-iCre	Lyz1	Alimentary system	Alimentary system-Small intestine	Paneth cells at the base of the small intestine	No
T052789	Lyz2-CreERT2	Lyz2	Immune system	Immune system-Granulocytes Immune system-Monocytes & macrophages Immune system-Dendritic cells	Myeloid cells (including monocytes, macrophages, granulocytes, mastocytes and some dendritic cells, etc)	No
T055071	Lyz2-P2A-iCre-P2A-EGFP	Lyz2	Immune system	Immune system-Granulocytes Immune system-Monocytes & macrophages Immune system-Dendritic cells	Myeloid cells (including monocytes, macrophages, granulocytes, mastocytes and some dendritic cells, etc)	No
T055107	Lyz2-iCre	Lyz2	Immune system	Immune system-Granulocytes Immune system-Monocytes & macrophages Immune system-Dendritic cells	Myeloid cells (including monocytes, macrophages, granulocytes, mastocytes and some dendritic cells, etc)	No
T050101	MKi67-rox-stop-rox-iCre	MKi67	Uncategorized	Uncategorized-Application scenary identified	Actively dividing cells	No
T053841	Mag-P2A-Dre	Mag	Nervous system	Nervous system-Supportive cells	Oligodendrocytes	No
T037362	Mcam-CreERT2-P2A	Mcam	Circulation system	Circulation system-Vascular smooth muscle Circulation system-Vascular/lymphatic endothelium	Mesenchymal stem cells, vascular endothelial cells, vascular smooth muscle cells	No
T058059	Mcpt8-P2A-iCre-T2A-EGFP	Mcpt8	Immune system	Immune system-Granulocytes	Basophils	No
T053520	Mki67-rox-stop-rox-CreERT2-P2A	Mki67	Uncategorized	Uncategorized-Application scenary identified	Actively dividing cells	No
T051136	Ms4a1-iCre	Ms4a1	Immune system	Immune system-T lymphocytes Immune system-B lymphocytes	Primarily on B cells and some Treg cells	No
T051032	Msx2-P2A-iCre-P2A-EGFP	Msx2	Reproductive system Motor & skeletal system	Reproductive system-Female reproductive organs reproductive organs Motor & skeletal system-Bone/cartilage	Skin, skull, developing limb fields/limb buds and their differentiated cells, oocytes and follicles	No
T052702	Muc2-P2A-iCre	Muc2	Alimentary system	Alimentary system-Small intestine	Goblet cells	No
T006806	Myf5-P2A-iCre	Myf5	Motor & skeletal system	Motor & skeletal system-Skeletal muscle	Skeletal muscle	No
T055034	Myh6-IRES-iCre	Myh6	Circulation system	Circulation system-Myocardium	Almost all mature cardiomyocytes	No
T057354	Ncam1-P2A-CreERT2	Ncam1	Nervous system	Nervous system-Hippocampus Nervous system-Cortex Nervous system-Supportive cells	Cortex, hippocampus, cerebellum, astrocytes	No
T050180	Nes-P2A-iCre	Nes	Nervous system	Nervous system-Hippocampus Nervous system-Cortex Nervous system-Thalamus/hypothalamus Nervous system-Brainstem Nervous system-Supportive cells	Central and peripheral Nervous system, neural precursor cells, oligodendrocyte precursor cells	No
T052684	Nfatc1-P2A-iCre	Nfatc1	Circulation system Motor & skeletal system	Circulation system-Others Motor & skeletal system-Bone/cartilage	Osteoclasts, endocardial cells	No
T006193	Nkx2-5-IRES-iCre	Nkx2-5	Circulation system	Circulation system-Myocardium	Cardiac crescent cells and cardiac ductal progenitor cells	No

STRAIN NO.	STRAIN NAME	PROMOTER	THEORETICAL ORGAN/SYSTEM EXPRESSION	SUBCLASSIFICATION	THEORETICAL LABELED CELL TYPE	PUBLISHED LITERATURE
T053687	Npsr1-IRES-iCre	Npsr1	Uncategorized	Uncategorized-Application under discovery	Npsr1+ cells, application under discovery	No
T006188	Npy-iCre	Npy	Nervous system	Nervous system-Corpus striatum Nervous system-Cortex Nervous system-Thalamus/hypothalamus Nervous system-Olfactory bulb	Ubiquitously expressed in cortex, with high activity in layer 6 in posterior cortical regions and in layers 4, 5, and 6 in anterior cortical regions. Expression is also enriched in the hypothalamus, thalamus, striatum, olfactory bulb and cerebellum	No
T056031	Nr2f2-IRES-iCre	Nr2f2	Uncategorized	Uncategorized-Application under discovery	Nr2f2+ cells, application under discovery	No
T052781	Nr4a2-P2A-CreERT2-IRES-EGFP	Nr4a2	Nervous system Endocrine system	Nervous system-Cortex Nervous system-Olfactory bulb	Expressed in pear-shaped nucleus and entorhinal area; also active in pituitary and adrenal gland	No
T055994	Nrp2-CreERT2	Nrp2	Nervous system Respiratory system Circulation system Endocrine system	Circulation system-Hematopoietic cell lineage Circulation system-Vascular/lymphatic endothelium Nervous system-Others	Intracranial neural crest cells and trunk neural crest cells; vascular & lymphatic endothelial cells; pancreatic islet cells; lung	No
T052683	Nrp2-iCre	Nrp2	Nervous system Respiratory system Circulation system	Circulation system-Hematopoietic cell lineage Circulation system-Vascular/lymphatic endothelium Nervous system-Others	Primitive cells, venous and lymphatic endothelial cells, sensory ganglia, lung	No
T056221	Olfm4-IRES-EGFPCreERT2	Olfm4	Alimentary system	Alimentary system-Small intestine	Intestinal stem cells	No
T005675	Otx2-iCre-P2A	Otx2	Nervous system Sensory organs	Nervous system-Hippocampus Nervous system-Cortex Nervous system-Thalamus/hypothalamus	Almost all ectoderm-derived brain regions, retina, craniofacial structures, etc.	No
T006593	Pcp2-iCre	Pcp2	Nervous system Sensory organs	Nervous system-Thalamus/hypothalamus	Purkinje cells in the cerebellum and hypothalamus; retinal bipolar neurons	No
T057581	Pdha2-GFPCre	Pdha2	Reproductive system	Reproductive system-Male reproductive organs	Testis	No
T055044	Pecam1-iCre-P2A-EGFP	Pecam1	Circulation system	Circulation system-Vascular/lymphatic endothelium	Endothelial cells	No
T005328	Pf4-P2A-iCre	Pf4	Circulation system	Circulation system-Hematopoietic cell lineage	Megakaryocytes and some hematopoietic stem cells	No
T050132	Phox2b-CreERT2	Phox2b	Nervous system Endocrine system	Nervous system-Others	Hindbrain, especially the dorsal motor nucleus of the vagus nerve, visceral motor neurons and gill motor neurons located in the parasympathetic nerve, nodal sensory ganglia and solitary bundle nucleus cells; adult mice also have Cre activity in the adrenal gland with induction	No
T057690	Pi16-P2A-CreERT2	Pi16	Urinary system		Urinary bladder	No
T053779	Postn-MerCreMer	Postn	Motor & skeletal system	Motor & skeletal system-Skeletal muscle	Myofibroblasts in injured tissue	No
T006206	Prdm1-P2A-iCre	Prdm1	Reproductive system Immune system	Reproductive system-Female reproductive organs reproductive organs Reproductive system-Male reproductive organs Immune system-B lymphocytes	Primordial germ cells, plasmocytes	No
T052700	Prl3d1-iCre	Prl3d1	Uncategorized	Uncategorized-Application scenary identified	Placental trophoblasts	No
T052711	Prok2-P2A-iCre	Prok2	Reproductive system	Reproductive system-Male reproductive organs	Testis	No
T053169	Psma8-P2A-CreGFP	Psma8	Reproductive system	Reproductive system-Male reproductive organs	Testis	No
T006208	Ptf1a-P2A-CreERT2	Ptf1a	Alimentary system	Alimentary system-Pancreas	Pancreas	No

STRAIN NO.	STRAIN NAME	PROMOTER	THEORETICAL ORGAN/SYSTEM EXPRESSION	SUBCLASSIFICATION	THEORETICAL LABELED CELL TYPE	PUBLISHED LITERATURE
T054004	Pth2-P2A-Cre	Pth2	Reproductive system	Reproductive system-Male reproductive organs	Testis	No
T049920	Pthlh-iCre	Pthlh	Motor & skeletal system	Motor & skeletal system-Bone/cartilage	Growth plate chondrocytes	No
T004861	Pvalb-IRES-iCre	Pvalb	Nervous system	Nervous system-Hippocampus Nervous system-Corpus striatum Nervous system-Cortex Nervous system-Thalamus/hypothalamus Nervous system-Brainstem	Expressed in restricted and/or sparse cells in the cerebellum, medulla, pons, midbrain, cortex, hippocampus, thalamus, and corpus striatum	No
T006190	Rax-iCre-P2A	Rax	Nervous system Sensory organs Endocrine system	Nervous system-Thalamus/hypothalamus Nervous system-Others	Developing retinal cells, hypothalamus and posterior pituitary gland.	No
T056032	Rora-IRES-iCre	Rora	Immune system Nervous system Sensory organs	Immune system-T lymphocytes Nervous system-Thalamus/hypothalamus	Widely expressed in brain, with high expression in the thalamus, cerebellum, and retina; activity in Purkinje cells and some CD4+ T cells	No
T054834	Rosa26-Alb-iCre-polyA	Alb	Liver		Hepatic cells	No
T050183	Rosa26-EIIA-iCre	EIIA	Ubiquitous		Ubiquitous expressed (expressed during early embryonic development)	No
T050182	Rosa26-SA-CreERT2	Rosa26	Ubiquitous		Ubiquitous expressed	No
T053975	Ruvbl2-P2A-iCre	Ruvbl2	Uncategorized	Uncategorized-Application under discovery	Ruvbl2+ cells, application under discovery	No
T005636	S100A8-iCre	hS100A8	Immune system	Immune system-Granulocytes Immune system-Monocytes & macrophages	Granulocytes, macrophages	No
T052706	Scnn1a-P2A-iCre	Scnn1a	Nervous system	Nervous system-Hippocampus Nervous system-Corpus striatum Nervous system-Cortex	Whole cortex, corpus striatum, hippocampus and cerebellum	No
T052916	Sfrp2-DreERT2-IRES-LacZ-polyA	Sfrp2	Motor & skeletal system	Motor & skeletal system-Bone/cartilage	Osteoblasts	No
T056443	Slc12a1-DreERT2-P2A-EGFP-T2A	Slc12a1	Urinary system		Kidney	No
T056832	Slc12a1-P2A-DreERT2-T2A-EGFP	Slc12a1	Urinary system		Kidney	No
T052991	Slc34a1-CreERT2-EGFP	Slc34a1	Urinary system		Renal proximal tubular stem cells	No
T006955	Slc6a3-iCre	Slc6a3	Nervous system	Nervous system-Cortex Nervous system-Thalamus/hypothalamus Nervous system-Brainstem	Dopaminergic neurons	No
T052999	Slc6a3-ires-iCre	Slc6a3	Nervous system	Nervous system-Cortex Nervous system-Thalamus/hypothalamus Nervous system-Brainstem	Dopaminergic neurons	No
T056087	Slit3-IRES-iCre	Slit3	Uncategorized	Uncategorized-Application under discovery	Slit3+ cells, application under discovery	No
T057018	Smpd3-3*Flag-IRES-EGFP-P2A-CreERT2	Smpd3	Uncategorized	Uncategorized-Application under discovery	Smpd3+ cells, application under discovery	No
T005679	Sohlh1-iCre	Sohlh1	Reproductive system	Reproductive system-Female reproductive organs reproductive organs	Primordial follicles	No

STRAIN NO.	STRAIN NAME	PROMOTER	THEORETICAL ORGAN/SYSTEM EXPRESSION	SUBCLASSIFICATION	THEORETICAL LABELED CELL TYPE	PUBLISHED LITERATURE
T056184	Sost-CreERT2	Sost	Motor & skeletal system	Motor & skeletal system-Bone/cartilage	Osteocytes	No
T051115	Sox1-P2A-iCre-P2A-EGFP	Sox1	Uncategorized Nervous system	Nervous system-Others Uncategorized-Application scenary identified	Neuroepithelial cells during embryonic development and their differentiation into mesenchymal stem cells (neural crest migration and differentiation), resulting in widespread cre activity	No
T050099	Sox2-rox-stop-rox-P2A-iCre	Sox2	Nervous system	Nervous system-Hippocampus Nervous system-Cortex Nervous system-Thalamus/hypothalamus Nervous system-Brainstem	Ectoderm-derived cells such as neural precursor cells and epithelial cells	No
T057842	Spata13-IRES-iCre	Spata13	Nervous system	Nervous system-Cortex Nervous system-Amygdala Nervous system-Spinal cord	Central amygdala, prefrontal cortex, spinal cord	No
T049832	Spp1-CreERT2-IRES-EGFP	Spp1	Urinary system		Kidney	No
T051545	Srf-iCre	Srf	Uncategorized	Uncategorized-Application under discovery	Srf+ cells, application under discovery	No
T052682	Tac1-P2A-iCre	Tac1	Nervous system	Nervous system-Thalamus/hypothalamus Nervous system-Olfactory bulb Nervous system-Brainstem	Para- and anterior olfactory bulbs, thalamus, VMH and midbrain structures (e.g. superior colliculus) and scattered cells in caudate nucleus, septum, hypothalamus, midbrain, hindbrain and cerebellum	No
T055339	Tagln-CreERT2	Tagln	Circulation system Alimentary system Reproductive system	Circulation system-Vascular smooth muscle Circulation system-Myocardium Alimentary system-Small intestine Alimentary system-Large intestine Alimentary system-Stomach Reproductive system-Female reproductive organs Reproductive system-Male reproductive organs	Smooth muscle cells, myocardial cells	No
T006862	Tagln-iCre	Tagln	Circulation system Alimentary system Reproductive system	Circulation system-Vascular smooth muscle Circulation system-Myocardium Alimentary system-Small intestine Alimentary system-Large intestine Alimentary system-Stomach Reproductive system-Female reproductive organs Reproductive system-Male reproductive organs	Smooth muscle cells, myocardial cells	No
T053636	Tcf21-RFP-P2A-iCre	Tcf21	Circulation system	Circulation system-Others	Epicardial cells; fibroblasts in lung, kidney, stomach, small intestine, etc.	No
T051252	Tcf7-P2A-CreERT2-IRES-EGFP	Tcf7	Immune system	Immune system-T lymphocytes	Primarily on CD8+ T cells in spleen and lymph node	No
T055033	Tek-P2A-iCre	Tek	Circulation system	Circulation system-Hematopoietic cell lineage Circulation system-Vascular/lymphatic endothelium	Endothelial cells in blood vessels, lymph vessel, endocardium and a few hematopoietic stem cells and blood cells	No
T036743	Tg(Acta2-iCre)	Acta2	Circulation system Alimentary system Reproductive system	Circulation system-Vascular smooth muscle Circulation system-Myocardium Alimentary system-Small intestine Alimentary system-Large intestine Alimentary system-Stomach Reproductive system-Male reproductive organs Reproductive system-Female reproductive organs	Myofibroblasts	No
T052679	Tg(Adipoq-CreERT2)	Adipoq	Adipose tissue		White adipose tissue, brown adipose tissue	No
T010826	Tg(Car1-iCre)	Car1	Alimentary system	Alimentary system-Large intestine Alimentary system-Small intestine	Epithelial cells in cecum and proximal colon, some small intestinal epithelial cells	No
T007005	Tg(Cd8a-iCre )	Cd8a	Immune system	Immune system-T lymphocytes	CD8+ cytotoxic T cells, CD4+ T cells (due to existance of CD4+CD8+ T cells during development)	No
T036859	Tg(Ckmm-iCre)	Ckmm	Circulation system Motor & skeletal system	Circulation system-Myocardium Motor & skeletal system-Skeletal muscle	Skeletal muscle and myocardial cells	No
T005639	Tg(Crx-iCre)	Crx	Nervous system Sensory organs	Nervous system-Others	Retina, pineal body	No
T009775	Tg(Cryaa-iCre)	Cryaa	Sensory organs		Lens epithelial cells, lensfibers	No
T010853	Tg(Foxp3-iCre)	Foxp3	Immune system	Immune system-T lymphocytes	Treg cells	No

STRAIN NO.	STRAIN NAME	PROMOTER	THEORETICAL ORGAN/SYSTEM EXPRESSION	SUBCLASSIFICATION	THEORETICAL LABELED CELL TYPE	PUBLISHED LITERATURE
T017624	Tg(Fzd5-iCre)	Fzd5	Alimentary system Sensory organs Reproductive system	Alimentary system-Stomach Alimentary system-Large intestine Alimentary system-Small intestine Alimentary system-Others Reproductive system-Male reproductive organs	Retinal cells; sublingual gland, esophagus, stomach, intestinal epithelial cells, intestinal villi and low activity in pancreas islet; prostate, testis。	No
T010833	Tg(Kap-iCre)	Kap	Urinary system		Kidney of male mice	No
T014734	Tg(Nr5a1-iCre)	Nr5a1	Reproductive system Endocrine system Nervous system	Reproductive system-Female reproductive organs reproductive organs Reproductive system-Male reproductive organs Nervous system-Thalamus/hypothalamus	Ventromedial hypothalamus, adrenal cortex, pituitary and gonad	No
T009779	Tg(Nrl-iCre)	Nrl	Sensory organs		Rod cells	No
T014859	Tg(Opn1mw-iCre)	Opn1mw(M-opsin)	Sensory organs		Cone cells (medium wavelength)	No
T010813	Tg(Opn1sw-iCre)	Opn1sw	Sensory organs		Cone cells (small wavelength)	No
T010829	Tg(Prox1-CreERT2)	Prox1	Circulation system Motor & skeletal system Sensory organs Liver	Circulation system-Vascular/lymphatic endothelium Circulation system-Myocardium Motor & skeletal system-Skeletal muscle	Lymphatic endothelial cells	No
T036868	Tg(Runx2-iCre-FRT)	Runx2	Motor & skeletal system	Motor & skeletal system-Bone/cartilage	Osteoblasts	No
T006589	Tg(S100a4-CreERT2)	S100a4	Uncategorized	Uncategorized-Application scenary identified	Stromal fibroblasts in the prostate, forestomach, breast, etc.	No
T009747	Tg(Sftpa1-iCre)	Sftpa1	Respiratory system		Lung	No
T052691	Tg(Sox2-iCre)	Sox2	Nervous system Sensory organs	Nervous system-Hippocampus Nervous system-Cortex Nervous system-Thalamus/hypothalamus Nervous system-Brainstem	Ectoderm-derived cells such as neural precursor cells and epithelial cells	No
T052681	Tg(Sp7-iCre)	Sp7	Motor & skeletal system	Motor & skeletal system-Bone/cartilage	Osteoblasts	No
T036984	Tg(Vsx2-iCre)	Vsx2	Sensory organs		Bipolar nerve cells	No
T050269	TgTn(pb-CAG-iCre)	CAG	Ubiquitous		Ubiquitous expressed	No
T053476	Tigit-P2A-EGFP-P2A-iCre	Tigit	Immune system	Immune system-T lymphocytes Immune system-NK cells	Some activated T cells, majority of NK cells	No
T050766	Tmem119-P2A-CreERT2	Tmem119	Nervous system	Nervous system-Supportive cells	Microglial cells	No
T050767	Tmem119-P2A-iCre	Tmem119	Nervous system	Nervous system-Supportive cells	Microglial cells, actual efficacy unknown due to non-specific expression during embryonic development	No
T015813	Trp63-CreERT2	Trp63	Urinary system Reproductive system	Reproductive system-Male reproductive organs	Epithelial cells in urogenital sinus, prostate and urinary bladder	No
T050096	Trp63-rox-stop-rox-P2A-iCre	Trp63	Urinary system Reproductive system	Reproductive system-Male reproductive organs	Epithelial cells in urogenital sinus, prostate and urinary bladder	No
T055395	Trpc4-T2A-iCre	Trpc4	Nervous system Circulation system Urinary system Motor & skeletal system	Nervous system-Hippocampus Circulation system-Myocardium Nervous system-Cortex Circulation system-Vascular smooth muscle Nervous system-Amygdala Nervous system-Others Circulation system-Vascular/lymphatic endothelium，Motor & skeletal system-Skeletal muscle	Widely expressed in cortex, hippocampus, amygdala, etc.;cardiovascular system including endothelial cells, smooth muscle and myocardial cells, skeletal muscle cells；kidney、pyramidal neurons and dorsal root ganglion	No

STRAIN NO.	STRAIN NAME	PROMOTER	THEORETICAL ORGAN/SYSTEM EXPRESSION	SUBCLASSIFICATION	THEORETICAL LABELED CELL TYPE	PUBLISHED LITERATURE
T052715	Tyr-CreERT2	Tyr	Uncategorized	Uncategorized-Application scenary identified	melanoblasts and melanocytes	No
T056298	Uchl1-P2A-CreERT2	Uchl1	Nervous system	Nervous system-Cortex Nervous system-Spinal cord	Corticospinal motor neurons, dorsal root ganglia, dynamoneure and other sensory neurons	No
T050812	Upk2-P2A-iCre	Upk2	Urinary system		Uroepithelial cells of the bladder and ureter	No
T038247	Uts2r-P2A-CreERT2	Uts2r	Uncategorized	Uncategorized-Application under discovery	Uts2r+ cells, application under discovery	No
T056544	Uts2r-P2A-Dre	Uts2r	Uncategorized	Uncategorized-Application under discovery	Uts2r+ cells, application under discovery	No
T052676	Vav1-iCre	Vav1	Circulation system	Circulation system-Hematopoietic cell lineage	Hematopoietic stem cells, almost all blood cells	No
T054065	Vim-rox-stop-rox-iCre	Vim	Uncategorized	Uncategorized-Application scenary identified	Expressed on cells in the endothelial-mesenchymal transition (EMT) process and can be used as a marker or conditional knockout for endothelial cells during migration, transdifferentiation, or spontaneous tumors.	No
T006191	Vip-iCre	Vip	Nervous system	Nervous system-Cortex Nervous system-Brainstem	Widely expressed in the brain, primarily in the cortex and restricted in the midbrain and hindbrain.	No
T053688	Vwa5b1-IRES-iCre	Vwa5b1	Reproductive system	Reproductive system-Male reproductive organs	Testis	No
T006194	Wfs1-P2A-iCre	Wfs1	Nervous system	Nervous system-Hippocampus Nervous system-Cortex Nervous system-Thalamus/hypothalamus	Highly expressed in the pyriform cortex and 2/3 layer of the cortex; hippocampus, striatum, thalamus, cerebellum and some cell populations in olfactory areas.	No
T010882	Zbtb7b-iCre	Zbtb7b	Immune system	Immune system-T lymphocytes Immune system-Monocytes Immune system-Macrophages	Bone marrow macrophages, CD4+ T cells	No