The Future is Flexible: Summary Substrate stiffness serves as a critical determinant of MSC behaviour, exerting profound effects on adhesion, proliferation, migration, and differentiation. Understanding
Different tissues and organs in the body have varying levels of matrix stiffness. These differences in stiffness are critical for the proper functioning of cells within their respective tissues.
In vitro three-dimensional (3D) cell cultures have been increasingly used for drug discovery, tissue engineering, cancer research, stem cell research and regenerative medicine.
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