Product Description
Achieve unprecedented control and reproducibility in your spheroid cultures
SphericalPlate 5D offers a revolutionary approach to 3D cell culture, delivering exceptional uniformity and physiological relevance. With its unique microwell design, this innovative plate enables the simultaneous generation of up to 750 standardized spheroids per well, and 9000 spheroids per 24-well plate.
Key Benefits:
- High throughput: Efficiently produce large numbers of uniform spheroids.
- Physiological relevance: Mimic in vivo conditions for accurate experimental results.
- Reproducibility: Generate consistent spheroid size and shape for reliable data.
- Scalability: Easily increase or decrease culture scale without compromising quality.
The Power of the Fifth Dimension:
SphericalPlate 5D goes beyond traditional 3D culture by focusing on cellular communication. Our specialized nanocoating and precisely engineered microwells create an optimal environment for spheroid formation, preventing unwanted cell attachment and promoting natural cell-to-cell interactions. This results in highly uniform, physiologically accurate spheroids that are ideal for a wide range of biological studies.
Publications
Perugini V, Santin M. A Substrate-Mimicking Basement Membrane Drives the Organization of Human Mesenchymal Stromal Cells and Endothelial Cells Into Perivascular Niche-Like Structures. Front Cell Dev Biol. 2021 Sep 28;9:701842. DOI: 10.3389/fcell.2021.701842
Schreyer L, Mittermeier C, et al. Tetraspanin 5 (TSPAN5), a Novel Gatekeeper of the Tumor Suppressor DLC1 and Myocardin-Related Transcription Factors (MRTFs), Controls HCC Growth and Senescence. Cancers (Basel). 2021 Oct 26;13(21):5373.  DOI: 10.3390/cancers13215373