Recombinant Human Interleukin-7 (rHu IL-7) plays a crucial role in T cell homeostasis. This cytokine is implicated in thymopoiesis since it sustains thymocyte proliferation and survival.

IL-7 regulates peripheral naive T cell survival by modulating the expression of the anti-apoptotic molecule Bcl-2, and sustains peripheral T cell expansion in response to antigenic stimulation. rHu IL-7 produced in E. coli is a single, non-glycosylated polypeptide chain that contains 153 amino acids and has a molecular mass of 17.41 kDa.

Features and Specifications:

• Custom packaging and sizes available
• Single-use syringe configuration
• Lyophilized or liquid format
• Pharmaceutical grade
• Sterile-filled
• Custom biological activity assays available
• Drug Master File available

Quality Statement

Akron’s cGMP Cytokines are manufactured, tested and released in compliance with relevant cGMP guidelines. USP Chapter ‹1043› “Ancillary materials for cell, gene and tissue-engineered products” has been followed in the design of these products.