Drug delivery

Mesenchymal Stem Cells as a Drug Delivery Vehicle for Brain Tumour

Cancer is a disease that can develop anywhere in our body as a result of excessive cell division. The location and cell types influence the etiology, symptoms, severity, and therapeutic approaches. In brain tumours, more than 75% of adults are affected by glioblastoma. The average survival rate is only two years after diagnosis, and the progression of therapeutic strategies is limited and challenging. These are mainly due to the blood-brain barrier (BBB) blockage, which makes intravenous chemotherapeutic compounds difficult to get through, and the relative rarity of this kind of cancer, which makes it difficult to attract pharmaceutical companies.

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Microfluidics is the technology of manipulating small volumes of fluids in channels with dimensions at the microscale – typically tens to hundreds of micrometres and is known as lab-on-a-chip.

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Exosome Research

Exosomes are nano-sized extracellular vesicles ranging 30-150 nanometers. They are readily released by most cells and can be found in all body fluids including plasma, serum, saliva, cerebrospinal fluid, urine and cell culture media.

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