High-Quality Lipid-Depleted Fetal Bovine Serum

Elevate your cell culture research with Biowest’s premium lipid-depleted fetal bovine serum (FBS). Specifically designed for applications sensitive to lipid content, our FBS is rigorously tested and quality-controlled to ensure optimal cell growth and performance.

Key Benefits:

Lipid-depleted formulation: Minimizes the influence of exogenous lipids on experimental outcomes.
Proven performance: Supports a wide range of cell lines and experimental conditions.
Stringent quality control: Manufactured under ISO 9001:2008 and ISO 13485:2012 standards.
Traceability: Sourced from BSE, FMD, and BVD-free regions.

Cell Lines Tested

The following cell lines are tested with the serum:

HELA -Cancer Cell/Human.
L929 -Fibroblast-Mouse/ As Macrophage
SP2/O-AG14 -Mouse/Lymphoma
MRC- 5 -Human/Lung.

Application

Autophagy studies
Lipid Metabolism & Arteriosclerosis Research

Trust Biowest for your critical cell culture needs.

We deliver Biowest solutions across South East Asia (Singapore, Thailand, Vietnam, Indonesia, Philippines, Myanmar) and Across China Only.

References

Beiyuan H., Tiantian Z., Wei Q. et al. Inhibition of EGFR Overcomes Acquired Lenvatinib Resistance Driven by STAT3–ABCB1 Signaling in Hepatocellular Carcinoma. Cancer Research. 2022; 82 (20): 3845–3857. Doi: https://doi.org/10.1158/0008-5472.CAN-21-4140

Article Snipped: “Cells were cultured in DMEM (Gibco) with 10% lipid depleted FBS (S181L, Biowest) for 24 hours”

Saliakoura, M., Sebastiano, M.R., Nikdima, I. et al. Restriction of extracellular lipids renders pancreatic cancer dependent on autophagy. J Exp Clin Cancer Res 41, 16 (2022). https://doi.org/10.1186/s13046-021-02231-y

Article Snipped: “AsPC-1 and SU68.86 were cultured in RPMI-1640 (Gibco), MiaPaCa-2, Hs766S, CFPAC-1 and PANC-1 cell lines were cultured in DMEM (Gibco); media were supplied with 10% FBS (Thermo Fisher) or delipidated FBS (via fumed silica precipitation method; Biowest #S181L)”

Elisabetta, V., Giovanni, L. B., Mariachiara, A. et al. Targeting of the lipid metabolism impairs resistance to BRAF kinase inhibitor in melanoma. Frontiers in Cell and Developmental Biology. 2022; 10. Doi; https://doi.org/10.3389/fcell.2022.927118

Article Snipped: “ Lipid starvation was carried out replacing FBS with lipid-depleted serum (S181L, Biowest, Voden Medical Instruments, Meda, Italy).”

Zhiwen, F., Ming, K., Min, L. et al. Brahma related gene 1 (Brg1) regulates cellular cholesterol synthesis by acting as a co-factor for SREBP2. Frontiers in Cell and Developmental Biology. 2020; 8. Doi: https://doi.org/10.3389/fcell.2020.00259

Article Snipped: “To induce SREBP2 activity, cells were cultured in the LDM1 media containing lipid-depleted fetal bovine serum (Biowest, cat# S181L).”

Marianne, R., Claire, H., Rebecca, M. et al. Trafficking of cholesterol to the ER is required for NLRP3 inflammasome activation. Journal of Cell Biology. (2018) 217 (10): 3560–3576. Doi: https://doi.org/10.1083/jcb.201709057

Article Snipped: “BMDMs were seeded into 24- or 12-well plates and incubated overnight in media containing 5% lipid-depleted serum (S181L; Biowest)”