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Fluorosurfactants

Fluorosurfactants

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Fluorosurfactant_Atlantis Bioscience
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Fluorosurfactants

High-purity fluorosurfactants for droplet microfluidics, ePCR, and single-cell encapsulation. Proven in peer-reviewed studies for stable, biocompatible emulsions.

Fluorosurfactant_Atlantis Bioscience

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High-Purity Fluorosurfactants for Droplet Microfluidics and Molecular Biology

Fluorosurfactants are specialized molecules that reduce interfacial tension between immiscible fluids—typically oil and water—to stabilize emulsions in droplet-based systems. In droplet microfluidics, they are critical for maintaining the integrity of water-in-oil droplets during thermal cycling, mechanical agitation, and molecular reactions.

These non-ionic fluorosurfactants are developed specifically for use in:

  • Emulsion PCR (ePCR)
  • Droplet-based single-cell and molecular assays
  • Encapsulation of sensitive biological materials such as DNA, RNA, proteins, and live cells

 

Key product advantages:

  • High purity and batch-to-batch reproducibility
  • Compatible with a wide range of enzymatic and biological systems
  • Stable droplet formation under rigorous conditions
  • Custom chemical modifications and packaging available
  • Expert technical and scientific support for troubleshooting and optimization

 

Ideal for researchers demanding high-performance surfactants for their microfluidic workflows, these reagents are a reliable foundation for achieving consistent, high-quality results.

When your experiments rely on precision droplets, don’t compromise on surfactant quality.

         

 

     
   
    MSDS:

Why Purchase from Atlantis Bioscience?

✅ Extensive Product Access: Choose from 1000+ top-tier products—viral vectors, cell culture media, and precision tools from trusted partners.

✅ Global Reach: We serve researchers across Asia, Europe, and South America with fast, reliable distribution.

✅ Expert Support: Our PhD-level team offers hands-on technical help to guide your research forward.

✅ A Partner for Life: We build long-term relationships—helping you find the right solutions at every step.

Explore the full line of fluorosurfactants at Atlantis Bioscience.
Reach out to request or consult with our technical specialists to find the right tools for your workflow.

email: [email protected]
website: www.atlantisbioscience.com/contact-us/

 

Variation

Neat (Un-dissolved) Fluorosurfactants

Product Size Catalogue Number
1g 008-FluoroSurfactant-1G
5g 008-FluoroSurfactant-5G
10g 008-FluoroSurfactant-10G
50g 008-FluoroSurfactant-50G
100g 008-FluoroSurfactant-100G
0.5kg 008-FluoroSurfactant-500G
1kg 008-FluoroSurfactant-1,000G

Fluorosurfactants Dissolved in Fluorinated Oils

Formulation Catalogue Number
50g of 2 wt% in HFE7500 008-FluoroSurfactant-2wtH-50g
50g of 2 wt% in FC40 008-FluoroSurfactant-2wtF-50G
500g of 2 wt% in HFE7500 008-FluoroSurfactant-2wtH-500G
500g of 2 wt% in FC40 008-FluoroSurfactant-2wtF-500G
20g of 5 wt% in HFE7500 008-FluoroSurfactant-5wtH-20G
20g of 5 wt% in FC40 008-FluoroSurfactant-5wtF-20G
200g of 5 wt% in HFE7500 008-FluoroSurfactant-5wtH-200G
200g of 5 wt% in FC40 008-FluoroSurfactant-5wtF-200G

Custom packaging of fluorosurfactants and emulsion oils available upon request.

Starter Kits

Contents Catalogue Number
008-FS in HFE7500 (10g at 5 wt%), 008-FS in FC40 (10g at 5 wt%), Neat HFE7500 (50g), Neat FC40 (50g) FS-Kit#1
Neat 008-FS (1g), Neat HFE7500 (60g), Neat FC40 (60g) FS-Kit#2

 

Functionalized Fluorosurfactants

Functionality Catalogue Number
Biotin FS-Biotin
BenzlGuanine FS-BG
Sugar FS-Sug
Fluorescein FluoreFS
Rhodamine FS-Rhodamine

Available Shipping Region

These fluorosurfactants are currently available for shipping exclusively across Asia through Atlantis Bioscience.

We proudly support researchers in the following regions:

  • Southeast Asia (Singapore, Malaysia, Thailand, Vietnam, Indonesia, Philippines)

  • East Asia (China, Hong Kong, Taiwan, South Korea, Japan)

  • South Asia (India, Pakistan, Bangladesh, Sri Lanka)

Orders placed from within Asia are fulfilled promptly with reliable logistics and dedicated customer support.

❗Please note: Shipping outside Asia is not available at this time. For international inquiries, kindly contact us for further assistance or alternative sourcing options.

Publications

008-FluoroSurfactant has been successfully applied in a wide range of droplet microfluidic and molecular biology studies. Below is a list of peer-reviewed publications that demonstrate its utility in single-cell analysis, droplet PCR, LAMP amplification, high-throughput drug screening, and more:

Dufossez, R., Ursuegui, S., Baudrey, S., Pernod, K., Mouftakhir, S., Oulad-Abdelghani, M., Mosser, M., Chaubet, G., Ryckelynck, M., & Wagner, A. (2023). Droplet Surface Immunoassay by Relocation (D-SIRE) for High-Throughput analysis of cytosolic proteins at the Single-Cell level. Analytical Chemistry, 95(9), 4470–4478. https://doi.org/10.1021/acs.analchem.2c05168

Erkamp, N. A., Oeller, M., Sneideris, T., Ausserwoger, H., Levin, A., Welsh, T. J., Qi, R., Qian, D., Lorenzen, N., Zhu, H., Sormanni, P., Vendruscolo, M., & Knowles, T. P. (2023). Multidimensional Protein Solubility Optimization with an Ultrahigh-Throughput Microfluidic Platform. Analytical Chemistry, 95(12), 5362–5368. https://doi.org/10.1021/acs.analchem.2c05495

Huang, Y., Sun, L., Liu, W., Yang, L., Song, Z., Ning, X., Li, W., Tan, M., Yu, Y., & Li, Z. (2023). Multiplex single-cell droplet PCR with machine learning for detection of high-risk human papillomaviruses. Analytica Chimica Acta, 1252, 341050. https://doi.org/10.1016/j.aca.2023.341050

Jahnke, K., Grubmüller, H., Igaev, M., & Göpfrich, K. (2021). Choice of fluorophore affects dynamic DNA nanostructures. Nucleic Acids Research, 49(7), 4186–4195. https://doi.org/10.1093/nar/gkab201

Kim, S. C., Clark, I. C., Shahi, P., & Abate, A. R. (2017). Single-Cell RT-PCR in Microfluidic Droplets with Integrated Chemical Lysis. Analytical Chemistry, 90(2), 1273–1279. https://doi.org/10.1021/acs.analchem.7b04050

Shi, Z., Dong, N., Lai, X., Yu, H., & Li, D. (2021). Centrifugal step emulsification microfluidics supporting droplet digital Loop-Mediated isothermal amplification (LAMP) of SARS-COV-2 N gene. 2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers), 976–979. https://doi.org/10.1109/transducers50396.2021.9495636

Wong, A. H., Li, H., Jia, Y., Mak, P., Da Silva Martins, R. P., Liu, Y., Vong, C. M., Wong, H. C., Wong, P. K., Wang, H., Sun, H., & Deng, C. (2017). Drug screening of cancer cell lines and human primary tumors using droplet microfluidics. Scientific Reports, 7(1). https://doi.org/10.1038/s41598-017-08831-z

Wu, H., Cao, X., Meng, Y., Richards, D., Wu, J., Ye, Z., & deMello, A. J. (2022). DropCRISPR: A LAMP-Cas12a based digital method for ultrasensitive detection of nucleic acid. Biosensors and Bioelectronics, 211, 114377. https://doi.org/10.1016/j.bios.2022.114377

FAQs

What are fluorosurfactants used for?

Fluorosurfactants are commonly used to stabilize water-in-oil emulsions in droplet-based microfluidics, emulsion PCR (ePCR), and single-cell encapsulation workflows. They reduce interfacial tension, allowing uniform droplet formation in systems that involve sensitive biological materials such as DNA, RNA, cells, and proteins.

These high-purity surfactants are essential for applications that require:

  • Stable emulsions under thermal cycling

  • Enzymatic compatibility

  • Reproducibility across batches

What oils are used in microfluidics?

In droplet microfluidics, fluorinated oils such as HFE7500 and FC40 are widely used as continuous phases. These oils provide chemical stability, low toxicity, and are well-suited for biological applications.

Our fluorosurfactants are pre-formulated in both HFE7500 and FC40 for convenience, with options like:

  • 2 wt% or 5 wt% surfactant concentrations

  • Multiple packaging volumes for scaling from research to production

What are the new materials for microfluidics in biology?

Newer materials in biological microfluidics include fluorosurfactants, hydrogels, and custom polymers that support more complex workflows like:

  • Single-cell RNA sequencing

  • 3D cell encapsulation

  • Droplet-based diagnostics

Fluorosurfactants in particular have become essential for biocompatible droplet formation without disrupting enzymes or fragile biological systems.

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