High-Purity Fluorosurfactants for Droplet Microfluidics and Molecular Biology
Fluorosurfactants are specialized molecules that reduce interfacial tension between immiscible fluids—typically oil and water—to stabilize emulsions in droplet-based systems. In droplet microfluidics, they are critical for maintaining the integrity of water-in-oil droplets during thermal cycling, mechanical agitation, and molecular reactions.
These non-ionic fluorosurfactants are developed specifically for use in:
- Emulsion PCR (ePCR)
- Droplet-based single-cell and molecular assays
- Encapsulation of sensitive biological materials such as DNA, RNA, proteins, and live cells
Key product advantages:
- High purity and batch-to-batch reproducibility
- Compatible with a wide range of enzymatic and biological systems
- Stable droplet formation under rigorous conditions
- Custom chemical modifications and packaging available
- Expert technical and scientific support for troubleshooting and optimization
Ideal for researchers demanding high-performance surfactants for their microfluidic workflows, these reagents are a reliable foundation for achieving consistent, high-quality results.
When your experiments rely on precision droplets, don’t compromise on surfactant quality.
MSDS:
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Explore the full line of fluorosurfactants at Atlantis Bioscience.
Reach out to request or consult with our technical specialists to find the right tools for your workflow.
email: [email protected]
website: www.atlantisbioscience.com/contact-us/
Variation
Neat (Un-dissolved) Fluorosurfactants
Product Size | Catalogue Number |
---|---|
1g | 008-FluoroSurfactant-1G |
5g | 008-FluoroSurfactant-5G |
10g | 008-FluoroSurfactant-10G |
50g | 008-FluoroSurfactant-50G |
100g | 008-FluoroSurfactant-100G |
0.5kg | 008-FluoroSurfactant-500G |
1kg | 008-FluoroSurfactant-1,000G |
Fluorosurfactants Dissolved in Fluorinated Oils
Formulation | Catalogue Number |
---|---|
50g of 2 wt% in HFE7500 | 008-FluoroSurfactant-2wtH-50g |
50g of 2 wt% in FC40 | 008-FluoroSurfactant-2wtF-50G |
500g of 2 wt% in HFE7500 | 008-FluoroSurfactant-2wtH-500G |
500g of 2 wt% in FC40 | 008-FluoroSurfactant-2wtF-500G |
20g of 5 wt% in HFE7500 | 008-FluoroSurfactant-5wtH-20G |
20g of 5 wt% in FC40 | 008-FluoroSurfactant-5wtF-20G |
200g of 5 wt% in HFE7500 | 008-FluoroSurfactant-5wtH-200G |
200g of 5 wt% in FC40 | 008-FluoroSurfactant-5wtF-200G |
Custom packaging of fluorosurfactants and emulsion oils available upon request.
Starter Kits
Contents | Catalogue Number |
---|---|
008-FS in HFE7500 (10g at 5 wt%), 008-FS in FC40 (10g at 5 wt%), Neat HFE7500 (50g), Neat FC40 (50g) | FS-Kit#1 |
Neat 008-FS (1g), Neat HFE7500 (60g), Neat FC40 (60g) | FS-Kit#2 |
Functionalized Fluorosurfactants
Functionality | Catalogue Number |
---|---|
Biotin | FS-Biotin |
BenzlGuanine | FS-BG |
Sugar | FS-Sug |
Fluorescein | FluoreFS |
Rhodamine | FS-Rhodamine |
Available Shipping Region
These fluorosurfactants are currently available for shipping exclusively across Asia through Atlantis Bioscience.
We proudly support researchers in the following regions:
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Southeast Asia (Singapore, Malaysia, Thailand, Vietnam, Indonesia, Philippines)
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East Asia (China, Hong Kong, Taiwan, South Korea, Japan)
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South Asia (India, Pakistan, Bangladesh, Sri Lanka)
Orders placed from within Asia are fulfilled promptly with reliable logistics and dedicated customer support.
❗Please note: Shipping outside Asia is not available at this time. For international inquiries, kindly contact us for further assistance or alternative sourcing options.
Publications
008-FluoroSurfactant has been successfully applied in a wide range of droplet microfluidic and molecular biology studies. Below is a list of peer-reviewed publications that demonstrate its utility in single-cell analysis, droplet PCR, LAMP amplification, high-throughput drug screening, and more:
Dufossez, R., Ursuegui, S., Baudrey, S., Pernod, K., Mouftakhir, S., Oulad-Abdelghani, M., Mosser, M., Chaubet, G., Ryckelynck, M., & Wagner, A. (2023). Droplet Surface Immunoassay by Relocation (D-SIRE) for High-Throughput analysis of cytosolic proteins at the Single-Cell level. Analytical Chemistry, 95(9), 4470–4478. https://doi.org/10.1021/acs.analchem.2c05168
Erkamp, N. A., Oeller, M., Sneideris, T., Ausserwoger, H., Levin, A., Welsh, T. J., Qi, R., Qian, D., Lorenzen, N., Zhu, H., Sormanni, P., Vendruscolo, M., & Knowles, T. P. (2023). Multidimensional Protein Solubility Optimization with an Ultrahigh-Throughput Microfluidic Platform. Analytical Chemistry, 95(12), 5362–5368. https://doi.org/10.1021/acs.analchem.2c05495
Huang, Y., Sun, L., Liu, W., Yang, L., Song, Z., Ning, X., Li, W., Tan, M., Yu, Y., & Li, Z. (2023). Multiplex single-cell droplet PCR with machine learning for detection of high-risk human papillomaviruses. Analytica Chimica Acta, 1252, 341050. https://doi.org/10.1016/j.aca.2023.341050
Jahnke, K., Grubmüller, H., Igaev, M., & Göpfrich, K. (2021). Choice of fluorophore affects dynamic DNA nanostructures. Nucleic Acids Research, 49(7), 4186–4195. https://doi.org/10.1093/nar/gkab201
Kim, S. C., Clark, I. C., Shahi, P., & Abate, A. R. (2017). Single-Cell RT-PCR in Microfluidic Droplets with Integrated Chemical Lysis. Analytical Chemistry, 90(2), 1273–1279. https://doi.org/10.1021/acs.analchem.7b04050
Shi, Z., Dong, N., Lai, X., Yu, H., & Li, D. (2021). Centrifugal step emulsification microfluidics supporting droplet digital Loop-Mediated isothermal amplification (LAMP) of SARS-COV-2 N gene. 2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers), 976–979. https://doi.org/10.1109/transducers50396.2021.9495636
Wong, A. H., Li, H., Jia, Y., Mak, P., Da Silva Martins, R. P., Liu, Y., Vong, C. M., Wong, H. C., Wong, P. K., Wang, H., Sun, H., & Deng, C. (2017). Drug screening of cancer cell lines and human primary tumors using droplet microfluidics. Scientific Reports, 7(1). https://doi.org/10.1038/s41598-017-08831-z
Wu, H., Cao, X., Meng, Y., Richards, D., Wu, J., Ye, Z., & deMello, A. J. (2022). DropCRISPR: A LAMP-Cas12a based digital method for ultrasensitive detection of nucleic acid. Biosensors and Bioelectronics, 211, 114377. https://doi.org/10.1016/j.bios.2022.114377
FAQs
What are fluorosurfactants used for?
Fluorosurfactants are commonly used to stabilize water-in-oil emulsions in droplet-based microfluidics, emulsion PCR (ePCR), and single-cell encapsulation workflows. They reduce interfacial tension, allowing uniform droplet formation in systems that involve sensitive biological materials such as DNA, RNA, cells, and proteins.
These high-purity surfactants are essential for applications that require:
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Stable emulsions under thermal cycling
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Enzymatic compatibility
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Reproducibility across batches
What oils are used in microfluidics?
In droplet microfluidics, fluorinated oils such as HFE7500 and FC40 are widely used as continuous phases. These oils provide chemical stability, low toxicity, and are well-suited for biological applications.
Our fluorosurfactants are pre-formulated in both HFE7500 and FC40 for convenience, with options like:
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2 wt% or 5 wt% surfactant concentrations
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Multiple packaging volumes for scaling from research to production
What are the new materials for microfluidics in biology?
Newer materials in biological microfluidics include fluorosurfactants, hydrogels, and custom polymers that support more complex workflows like:
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Single-cell RNA sequencing
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3D cell encapsulation
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Droplet-based diagnostics
Fluorosurfactants in particular have become essential for biocompatible droplet formation without disrupting enzymes or fragile biological systems.