CELLDATA RNAstorm™ 2.0 FFPE RNA Extraction Kit

The CELLDATA RNAstorm™ 2.0 FFPE RNA Extraction Kit delivers up to 30-fold higher RNA yield and 2-fold higher DV200 values compared to conventional methods, ensuring superior performance for RNA-seq, qPCR, and gene expression studies.

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High-Yield, High-Integrity RNA Extraction from FFPE Samples with CAT5™ Technology

RNA extraction from FFPE (formalin-fixed, paraffin-embedded) tissue is notoriously difficult, often yielding fragmented, low-quality RNA unsuitable for downstream applications. The CELLDATA RNAstorm™ 2.0 FFPE RNA Extraction Kit overcomes these challenges with proprietary CAT5™ technology, which reverses formaldehyde crosslinking under mild conditions to release RNA of higher integrity.

Compared to other FFPE RNA extraction methods, RNAstorm™ 2.0 delivers 3- to 30-fold higher RNA yields and significantly improves RNA integrity, as reflected by a 2-fold increase in DV200 (% RNA >200 nt). The result is RNA that is more amplifiable and better suited for downstream workflows such as RNA-seq, qPCR, microarray, and gene expression analysis.

Key Features

CAT5™ chemical reversal technology efficiently removes formaldehyde-induced crosslinks.
Higher yields of amplifiable RNA (3–30× improvement over competitor methods).
Superior RNA quality: 2× increase in DV200 and higher RIN scores.
Gentle protocol: mild conditions, no harsh solvents.
Improved downstream performance: enables more reliable reverse transcription, sequencing, and array analysis.
User-friendly workflow: simple spin column-based extraction.

Applications

RNA extraction from FFPE samples (archival tissues, clinical biopsies, research collections)
RNA-seq and transcriptome profiling
qPCR and gene expression analysis
Microarray-based assays
Biomarker discovery in oncology, neuroscience, immunology, and pathology research

Advantages of CAT5™ Technology

Higher RNA yields from FFPE tissues (archival blocks dated as far back as 1976 have shown significant improvements).
Improved RNA integrity: reduced fragmentation, better amplifiability.
Enhanced downstream performance in PCR, microarray, and next-generation sequencing (NGS).