BioMab Circulating Tumour Cells (CTC) Enrichment Kit

BioMab Circulating Tumour Cells (CTC) Enrichment Kit

BioMab Circulating Tumour Cells (CTC) Enrichment Kit

Our CTC enrichment kit is the most sensitive platform with high specificity – EpCAM antibody with the highest binding affinity (Kd < 10-12).

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Description

Product Description

Circulating Tumour Cells (CTC)

CTC is rare (1 in 109 cells) – detecting CTCs with high sensitivity and specificity is a major challenge. Our CTC enrichment kit is the most sensitive platform with high specificity – EpCAM antibody with the highest binding affinity (Kd < 10-12).

  • It can be used with liquid Biopsy – detecting cancers through a simple blood draw
  •  Clinical data in breast, colorectal, gastric, head & neck, non-small cell lung cancers across 4 notable teaching hospitals in Taiwan.
  •  2 paper citations by CellSearch Inventor (Professor Leon Terstappen)
  • —  Detects CTCs in >95% of patients enrolled (n > 125)
  • —  Capturing live CTCs for culturing (success rate reaching ~96%, n = 50)
  • —  Successfully performed NGS on CTCs captured from patients
  • —  Can capture CTC with low EpCAM Expressions (e.g., CTCs with EMT, MDA-MB-231)

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[accordion title=”CTC Competitor Comparison”]

Company Technology Platform Sensitivity Specificity Culturing & Sequencing Capturing Clusters Pricing
BioMab Anti-EpCAM Antibody (EpCAM Ab, Kd < 10^-12)
conjugated with magnetic beads

 

Anti-EpCAM Antibody highest binding affinity in
the world

High High Low
Competitor A Microfluidics coated with antibodies Low Low X X Low
Competitor B Anti-EpCAM antibody conjugated with magnetic beads Low High X X High
Competitor C Microfluidics plus anti-EpCAM antibody conjugated
with magnetic beads
Low High X X High
Competitor D Microfluidics based on cell size High Low High
Competitor E Antibody and FISH probes Low High X Low

[/accordion]