Anti-SARS-CoV-2 Spike mAb (CR3022)
Anti-SARS-CoV-2 Spike mAb (CR3022)
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Anti-SARS-CoV-2 Spike mAb (CR3022) is a a CHO cell derived human monoclonal IgG1 antibody. It binds to both S1 domain of SARS-CoV/SARS-CoV-2 Spike protein.
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| Description | Anti-SARS-CoV-2 Spike mAb (CR3022) is a a CHO cell derived human monoclonal IgG1 antibody. It binds to both S1 domain of SARS-CoV/SARS-CoV-2 Spike protein. |
| In vitro | CR3022 recognizes a cryptic epitope that is only accessible when S protein is in open” conformations[1]. CR3022 binds more tightly to SARS-CoV because its epitope contains a glycan not present in SARS-CoV-2[2]. |
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