Highest anti-EpCAM binding affinity in the world.

EpCAM (CD326), also known as tumour-associated calcium signal transducer 1 (TACSTD1) is a type I transmembrane glycoprotein of 39-42 kDa, consisting of 314 amino acids.

EpCAM is expressed on the basolateral membrane of all simple, pseudo-stratified, and transitional epithelia. It negatively regulates the expression of p53 and p21 and promotes tumour cell growth, colony formation, migration and invasion.

Anti-EpCAM monoclonal antibodies have shown promise as a diagnostic tool and in antibody-based immunotherapies for a spectrum of malignancies. Comparative assay among different anti-EpCAM mAbs has shown that BioMAb’s BMI-EPCAMAb3 has the highest binding affinity, and provides better sensitivity and specificity for downstream assays.

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· Western Blot

· ELISA

· IFA

· IHC

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• Product name:  Anti-EpCAM Monoclonal Antibody
• Size: 100ug
• Gene: EpCAM
• Purity: IgG purified
• Isotype: IgG2b
• Immunogen: Purified EpCAM
• Localization: Cell membrane
• Host: Mouse
• Clone: EpAb3-5
• Clonality: Monoclonal
• Category: Primary
• Target species: Human
• Specificity:  This antibody has specificity for EpCAM
• Species specificity: Cross-reacts with Human. Does not cross react with mouse
• Dilution range:  Flow Cytometry and ELISA:  0.01 to 1 μg/ml; WB, IHC and  IF:  0.1 to 1 μg/ml
• Form:  Liquid (PBS (pH 7.4) with 0.09% NaN₃)
• Conjugate: unconjugated
• Shipping and storage: 2-8°C, DO NOT FREEZE

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