Human Umbilical Mesenchymal Stem Cell-Derived Extracellular Vesicles

Human Umbilical Mesenchymal Stem Cell-Derived Extracellular Vesicles

JOT-HUMSC-EV-01 provides lyophilised extracellular vesicles from human umbilical MSCs, isolated by ultracentrifugation and validated by NTA and TEM.

JOT-HUMSC-EV-01 product image

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SKU: JOT-HUMSC-EV-01-01F / 02 / 03 Categories: Tags: Brand:

Human Umbilical MSC EVs with Verified Size and Morphology for Consistent Results

JOT-HUMSC-EV-01 series provides extracellular vesicles (EVs) derived from human umbilical cord mesenchymal stem cells (hUCMSCs). The parental cells are a well-established source known for producing EVs with regenerative and signalling potential.

EVs are isolated using ultracentrifugation, a standard method that yields highly enriched vesicle populations. Each batch is characterised by nanoparticle tracking analysis (NTA) and transmission electron microscopy (TEM) to confirm particle size distribution (80–150 nm) and spherical morphology.

Supplied in lyophilised format, these EVs are stable for up to 36 months and can be reliably reconstituted in saline or hyaluronic acid for downstream research.

Key Features & Benefits

  • Defined Source: Derived from human umbilical cord mesenchymal stem cells (hUCMSCs)
  • Reliable Isolation: Prepared by ultracentrifugation, ensuring EV enrichment
  • Particle Validation: NTA and TEM confirm size distribution and morphology (80–150 nm, spherical vesicles)
  • Flexible Formats: Available in 3 particle counts (1E+10, 5E+9, 2E+9)
  • Long-Term Stability: Lyophilised (freeze-dried) with a 36-month shelf life
  • Reconstitution Protocol: Compatible with saline or hyaluronic acid, ready for research use

 

Applications

  • Extracellular Vesicle Biology Research
  • Intercellular Communication Studies
  • Exosome Standardisation & Controls
  • Preclinical Exploratory Research
  • Method Development

 

Size

  • JOT-HUMSC-EV-01-01F: 1 × 10¹⁰ particles
  • JOT-HUMSC-EV-01-02: 5 × 10⁹ particles
  • JOT-HUMSC-EV-01-03: 2 × 10⁹ particles

 

Note: These products are distributed only in Singapore and Thailand.

Product Specification

Specification Details
Product Name Human Umbilical Mesenchymal Stem Cell-Derived Extracellular Vesicles
Product SKU JOT-HUMSC-EV-01-01F / 02 / 03
Origin Human umbilical cord mesenchymal stem cells
Particle Count 1 × 10¹⁰ (01-01F), 5 × 10⁹ (01-02), 2 × 10⁹ (01-03)
Format Lyophilised (freeze-dried)
Shelf Life (lyophilised) 36 months
Stability after reconstitution 1 month at –20 °C; up to 6 months at –80 °C (avoid freeze–thaw cycles)
Characterisation NTA (size distribution), TEM (morphology)
Reconstitution Dissolve in saline or hyaluronic acid; vortex for 60 seconds
For Research Use Only Yes

Proven Performance

Morphological characterization (Left):Transmission electron microscopy (TEM) was used to characterize
the morphology and particle size of EVs.
Particle size analysis (Right): Particle size distribution is analyzed using nanoparticle tracking analysis (NTA) methods.
Morphological characterization (Left): Transmission electron microscopy (TEM) was used to characterize the morphology and particle size of EVs. Particle size analysis (Right): Particle size distribution is analyzed using nanoparticle tracking analysis (NTA) methods.

 

Before (left) and three months after (right) treatment using umbilicalcord mesenchymal stem cells derived exosomes.
Before (left) and three months after (right) treatment using umbilical cord mesenchymal stem cells derived exosomes.

 

Before (left) and three months after (right) treatment using umbilical cord mesenchymal stem cells derived exosomes.
Before (left) and three months after (right) treatment using umbilical cord mesenchymal stem cells derived exosomes.