Highly Purified Nanocarriers for Therapeutic Delivery and EV Research

JOT-HRBCEV-A1 contains a highly purified, homogeneous population of extracellular vesicles (EVs) derived from human red blood cells (RBCs). These vesicles, 50–250 nm in size, are obtained from pre-isolated RBCs via a rigorous purification workflow that removes contaminants such as lipoproteins and serum proteins, ensuring exceptional purity.

RBCEVs are naturally biocompatible and carry RNA, protein, and lipid cargo reflective of their parental cells. They are ideal for therapeutic cargo delivery, nanomedicine development, and as positive controls in EV-related experiments. Detection is possible via anti-GPA antibodies or EV-specific fluorescent dyes.

Key Features & Benefits

• ✅ High Purity: Free from lipoproteins, serum proteins, and other co-elutants

• ✅ Defined Size Range: Homogeneous distribution of ~50–250 nm

• ✅ Versatile Applications: Suitable for drug delivery, biomarker research, and EV assay controls

• ✅ Stable Formulations: Available as lyophilised powder or frozen suspension

• ✅ Flexible Detection: Compatible with anti-GPA antibodies and EV dyes

Formulation Options:

• Lyophilised powder: 1–1.5 × 10¹¹ particles per vial

• Frozen suspension: 1–10 × 10⁹ particles/µL (exact concentration on vial label)

Note: These products are distributed only in Singapore and Thailand.