Traditional knock-in animal models for coronavirus research are time-consuming, labor-intensive, and resource-demanding. Our pre-made hACE2 AAV vectors offer a rapid and efficient solution to accelerate your research. It is a powerful tool for modeling coronavirus infection and evaluating potential therapeutic interventions. By delivering the human ACE2 (hACE2) receptor gene to specific tissues, these vectors enable the study of viral entry, replication, and pathogenesis.

Advantages of Packgene’s AAV-hACE2 Animal Models:

• Rapid Model Generation: Significantly faster than traditional knock-in models.
• Tissue-Specific Expression: Target specific tissues, such as the lung, for accurate modeling.
• Stable and Long-Term Expression: Consistent hACE2 expression over time.
• Reduced Animal Numbers: Fewer animals required for experiments, improving efficiency and reducing costs.

Applications:

• Virus Entry and Replication Studies: Investigate the mechanisms of viral entry and replication.
• Drug Discovery and Development: Screen for antiviral drugs and vaccines.
• Pathogenesis Studies: Understand the underlying mechanisms of disease progression.

Contact Us